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BSHT 2022 ASM report

Dr Nikki Mutch, President of the BSHT and the BSHT committee were delighted to welcome back 110 attendees to their BSHT Annual Scientific meeting in person held at P&J Live in Aberdeen from 26-28 January 2022.

For the first time we organised an ECR event on the night preceding the conference.  We delivered an insight into various stages of the academic career path, including applying for postdoc and fellowship positions, applying for grants and forming collaborations.

The main conference included 6 plenary talks. Professor Steve Watson gave an excellent description of novel platelet GPVI ligands. Dr Nicola Curry, gave a fascinating insight into the dysregulation of the haemostatic system during trauma induced coagulopathy. Dr Catherine Bagot gave a timely overview into the development of COVID-19 vaccine-induced thrombocytopenia and thrombosis. Dr Matthew Harper enthusiastically described the development of a model of thrombus formation under flow, Professor Helen Philippou presented on novel inhibitors of the contact activation coagulation pathway and Professor Beverly Hunt gave an insightful update on coagulopathy in COVID-19. 

Highlights included an ‘emerging fellows’ talk by Dr Fraser Macrae on the formation and protective role of fibrin films on blood clots and a talk by Megan Simpson on the hypofibrinolytic state induced in COVID-19 patients which correlates with disease severity. This timely research won the Biochemical Society sponsored Scientist in training prize. An exciting theme throughout the conference were the topical presentations on COVID-19 and vaccine related thrombotic pathologies, their underlying mechanisms and treatment strategies being developed to tackle them. 

Overall, the BSHT 2022 delivered highly interesting, timely and impressive research from across the UK and provided ECRs from the society an excellent platform to present their research and develop their careers.

BSHT 2022 attendees
BSHT2022 attendees
Awardees of the Scientist in Training Award: 
BSHT2022 Scientist in Training presenters

(photographed left to right)

HSP47 regulates collagen structure and synthesis by megakaryocytes  
Gemma Little (Reading)

Fibrin Film and its Interactions with Red Blood Cells and Platelets   
Ghadir Alkarithi (Leeds)

Neutrophils and NETs Produce Clots with Different Types of Fibrin Fibers 
Yu Shi  (Leeds)

Shear-induced platelet reactivity in native blood assessed at the point-of-care correlates with thrombin generation in patients with myocardial infarction 
Rahim Kanji (London)

Plasminogen Activator Inhibitor-1 and its cofactor vitronectin induce a hypofibrinolytic state in COVID-19 disease which correlates with disease severity 
Megan Simpson  (Aberdeen)

Winner of the poster prize
BSHT2022 poster winner - Louis de Bernard 2jpg

Tranexamic acid has a direct impact on the structure of the fibrin network
Louis de Bernard (Oxford)

Poster runner up prize
BSHT2022 poster runner up - Safa Gayes

Using CRISPR/Cas9 to investigate the structure/function relationship of PLC𝜸2 in platelets
Safe Gayes (Reading)

3rd Joint Meeting of ISFP & PA 2022

3rd Joint Meeting of the International Society for Fibrinolysis and Proteolysis & Plasminogen Activation workshop 2022 

ISFP&PA 2022

The upcoming 3rd Joint Meeting of the International Society for Fibrinolysis and Proteolysis & Plasminogen Activation workshop 2022 (ISFP & PA 2022) which will be held in Caen (Normandie) on September 5th – 9th 2022. The meeting program covers the more recent advances in this field of research from basic to translational research and features an exciting compilation of two plenary and 10 SOA lectures.  Selected abstracts will be included in the main program as short talks (43 expected). The ISFP created “D. Collen Young Investigator Awards” from top five abstracts from young investigators.    

Full details see https://www.cyceron.fr/isfp/

Download Flier

Call for BSHT Summer Studentship scheme 2022 applications

For the 5th year the BSHT is proud to offer BSHT summer studentship scheme in 2022.
 
The scheme is able to run again this year with 3 studentships being awarded for a duration of 8-10 weeks (up to an additional 2 students may be considered depending on the quality of the applications).
 
The students will receive £150 per week and the host lab £500 running expenses.
 
Please send a brief outline of the project (no more than 2 pages) including background, aims and experimental plan, which should be completed by the supervisor with a named student.  The CV of the named student should also be included.
 
Applications should be emailed to both:
catherine.bagot@ggc.scot.nhs.uk; n.j.mutch@abdn.ac.uk
 
The closing date for this year is 17:00 hrs on Thursday 31 March 2022  with notification of award by Friday 29 April 2022.

BSHT bursaries to attend ISTH – July 2022

The ISTH congress this year is being hosted in London from 9-13 July 2022
Find out more

BSHT will be supporting BSHT members to attend the ISTH congress 2022 in London, with up to £25,000 worth of bursaries being made available to those presenting oral and/or poster presentations.

To be eligible to apply for a BSHT bursary award at ISTH 2022, applicants must;
 
Be the presenting author on an abstract accepted for an oral or poster presentation to the ISTH
and
Be either;
– a paid up member of the BSHT 
– a student of any sort (e.g. PhD/MD/MSc/BSc) being supervised by a paid up member of the BSHT
and
Have attended a BSHT meeting in the past 2 years (not necessary for student applicants)
and
Not have a substantive or tenured academic/clinical position

Download Application Form
 
Applicants should email the Treasurer, Prof Neil Morgan , with a completed application form,  a brief CV, as well as a copy of the abstract submitted.

Deadline for applications
17:00 hrs – Thursday 31 March 2022

Congratulations to the awardees at the BSHT Scientific Meeting 2022

Awardees of the Scientist in Training Award: 

BSHT2022 Scientist in Training presenters

1 Fibrin Film and its Interactions with Red Blood Cells and Platelets   
Ghadir Alkarithi (Leeds)

2  Neutrophils and NETs Produce Clots with Different Types of Fibrin Fibers 
Yu Shi  (Leeds)

3 HSP47 regulates collagen structure and synthesis by megakaryocytes  
Gemma Little (Reading)

4 Shear-induced platelet reactivity in native blood assessed at the point-of-care correlates with thrombin generation in patients with myocardial infarction 
Rahim Kanji (London)

5 Plasminogen Activator Inhibitor-1 and its cofactor vitronectin induce a hypofibrinolytic state in COVID-19 disease which correlates with disease severity 
Megan Simpson  (Aberdeen)

Winner of the poster prize

BSHT2022 poster winner - Louis de Bernard 2jpg

Tranexamic acid has a direct impact on the structure of the fibrin network
Louis de Bernard (Oxford)

Poster runner up prize

BSHT2022 poster runner up - Safa Gayes

Using CRISPR/Cas9 to investigate the structure/function relationship of PLC𝜸2 in platelets
Safe Gayes (Reading)

BSHT Annual meeting 2022